REDMILE GROUP LLC
Q4 2021 Form 13-F

SAN FRANCISCO, CALIFORNIA
CIK 0001425738 · CRD 143606 · SEC-registered investment adviser
$4.4B Reported Value Total

REDMILE GROUP reports 24 total accounts under management (AUM). There are 24 discretionary accounts valued at $14,344,486,253, and 0 non-discretionary accounts.

Source: Form ADV filed * Note that certain holdings are exempt from Form 13-F reporting, so the AUM totals may be greater than the Form 13-F total.
SEC Registered Discretionary Manager
Private funds (Form ADV)
27 funds · $7.7B gross asset value
Hedge Fund: $5.4B · Venture Capital Fund: $1.2B · Private Equity Fund: $1.1B
Source: Form ADV filed 2026-08-28
Reported value
$4.4B
Quarter over quarter
-15.6%
Holdings
71
Top-10 concentration
53.3%

Key People

Form ADV owners & control persons
Jeremy Charles Green
MANAGING MEMBER
Michael Stewart Lee
MANAGING DIRECTOR
Bryan Ranney Crapo
CHIEF OPERATING OFFICER

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Q4 2021 13F record

Q4 2021 13F filing summary

Q4 2021 Form 13F portfolio summary
Period of report December 31, 2021
Filed February 14, 2022
Form 13F-HR
Reported value $4.4B
Positions 71
Change in reported value -23.3%
New positions 8
Exited positions 12
Position turnover 24.1%
Top-10 concentration 53.3%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 14, 2026
39 $1.5B
Q1 2026 13F
Filed May 15, 2026
35 $1.5B
Q4 2025 13F
Filed Feb 17, 2026
34 $1.4B
Q3 2025 13F
Filed Nov 14, 2025
40 $1.0B
Q2 2025 13F
Filed Aug 14, 2025
48 $939.6M
Q1 2025 13F
Filed May 15, 2025
56 $1.1B
Q4 2024 13F
Filed Feb 14, 2025
62 $1.4B
Q3 2024 13F
Filed Nov 14, 2024
63 $1.7B
Q2 2024 13F
Filed Aug 14, 2024
63 $1.7B
Q1 2024 13F
Filed May 15, 2024
77 $2.7B
Q4 2023 13F
Filed Feb 14, 2024
70 $2.8B
Q3 2023 13F
Filed Nov 14, 2023
68 $2.1B
Q2 2023 13F
Filed Aug 14, 2023
72 $2.6B
Q1 2023 13F
Filed May 15, 2023
76 $2.3B
Q4 2022 13F
Filed Feb 14, 2023
69 $2.4B
Q3 2022 13F
Filed Nov 14, 2022
70 $2.6B
Q2 2022 13F
Filed Aug 15, 2022
71 $2.6B
Q1 2022 13F
Filed May 16, 2022
70 $3.2B
Q4 2021 13F
Filed Feb 14, 2022
71 $4.4B
Q3 2021 13F
Filed Nov 15, 2021
75 $5.7B

33 earlier quarters on file — choose one from the quarter menu above.

Top 20 holdings · Q4 2021

Largest Q4 2021 13F positions by reported value
# Holding Reported value % of portfolio
1 FATE FATE THERAPEUTICS INC $758.1M 17.24%
2 FOLD AMICUS THERAPEUTICS INC $262.4M 5.96%
3 SNCE SCIENCE 37 HOLDINGS INC $247.0M 5.62%
4 ARGX ARGENX SE $182.7M 4.15%
5 LIVN LIVANOVA PLC $179.9M 4.09%
6 KYMR KYMERA THERAPEUTICS INC $164.3M 3.74%
7 ADCT ADC THERAPEUTICS SA $150.5M 3.42%
8 BEAM BEAM THERAPEUTICS INC $150.3M 3.42%
9 KRYS KRYSTAL BIOTECH INC $127.4M 2.9%
10 SKIN THE BEAUTY HEALTH COMPANY $122.8M 2.79%
11 REPL REPLIMUNE GROUP INC $104.8M 2.38%
12 ATRA ATARA BIOTHERAPEUTICS INC $101.5M 2.31%
13 IGMS IGM BIOSCIENCES INC $97.8M 2.22%
14 NRIX NURIX THERAPEUTICS INC $85.6M 1.95%
15 CLDX CELLDEX THERAPEUTICS INC NEW $83.7M 1.9%
16 ABSI ABSCI CORPORATION $65.9M 1.5%
17 VERV VERVE THERAPEUTICS INC $63.0M 1.43%
18 RGNX REGENXBIO INC $62.0M 1.41%
19 IMGN IMMUNOGEN INC $61.3M 1.39%
20 SRRK SCHOLAR ROCK HLDG CORP $60.8M 1.38%

Values as reported on the Q4 2021 Form 13F. Every position is in the holdings table below.

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