PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC
Q2 2026 Form 13-F

SAN FRANCISCO, CALIFORNIA
CIK 0001844645 · CRD 287988 · Exempt reporting adviser
Holdings reported by Nan Fung Group Holdings Ltd since Q2 2021
Consolidated report · includes 1 manager since Q4 2020
$307.8M Reported Value Total
Exempt Reporting Adviser
Source: Form ADV filed 2026-06-25
Reported value
$307.8M
Quarter over quarter
-2.0%
Holdings
13
Top-10 concentration
95.1%

Filing Structure

Reports holdings for

Holdings reported by

Key People

Named on the latest Form 13-F filing — not necessarily an owner
Robert Hopfner
Managing Partner

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Q2 2026 13F record

Q2 2026 13F filing summary

Q2 2026 Form 13F portfolio summary
Period of report June 30, 2026
Filed August 13, 2026
Form 13F-HR
Reported value $307.8M
Positions 13
Change in reported value +10.0%
New positions 1
Exited positions 1
Position turnover 14.3%
Top-10 concentration 95.1%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 13, 2026
13 $307.8M
Q1 2026 13F
Filed May 14, 2026
13 $279.8M
Q4 2025 13F
Filed Feb 13, 2026
12 $258.7M
Q3 2025 13F
Filed Nov 13, 2025
10 $173.0M
Q2 2025 13F
Filed Aug 13, 2025
12 $161.3M
Q1 2025 13F
Filed May 14, 2025
11 $123.6M
Q4 2024 13F
Filed Feb 13, 2025
11 $148.1M
Q3 2024 13F
Filed Nov 13, 2024
11 $168.5M
Q2 2024 13F
Filed Aug 13, 2024
10 $130.1M
Q1 2024 13F
Filed May 14, 2024
11 $155.6M
Q4 2023 13F
Filed Feb 13, 2024
13 $394.2M
Q3 2023 13F
Filed Nov 13, 2023
13 $250.7M
Q2 2023 13F
Filed Aug 11, 2023
11 $303.3M
Q1 2023 13F
Filed May 12, 2023
11 $242.9M
Q4 2022 13F
Filed Feb 13, 2023
10 $230.0M
Q3 2022 13F
Filed Nov 10, 2022
11 $273.7M
Q2 2022 13F
Filed Aug 12, 2022
11 $198.5M
Q1 2022 13F
Filed May 13, 2022
11 $211.4M
Q4 2021 13F
Filed Feb 14, 2022
10 $239.2M
Q3 2021 13F
Filed Nov 15, 2021
9 $282.9M

3 earlier quarters on file — choose one from the quarter menu above.

Top 13 holdings · Q2 2026

Largest Q2 2026 13F positions by reported value
# Holding Reported value % of portfolio
1 PCVX VAXCYTE INC $82.9M 26.92%
2 ARQT ARCUTIS BIOTHERAPEUTICS INC $33.2M 10.78%
3 TRVI TREVI THERAPEUTICS INC $32.5M 10.56%
4 AVLN AVALYN PHARMACEUTICALS INC $31.8M 10.34%
5 EVMN EVOMMUNE INC $25.6M 8.32%
6 MPLT MAPLIGHT THERAPEUTICS INC $21.9M 7.12%
7 OCS OCULIS HOLDING AG $20.9M 6.79%
8 BIOA BIOAGE LABS INC $16.0M 5.2%
9 IMNM IMMUNOME INC $15.5M 5.04%
10 ZBIO ZENAS BIOPHARMA INC $12.5M 4.05%
11 AVTX AVALO THERAPEUTICS INC $8.0M 2.61%
12 RLYBZZZZ RALLYBIO CORP $4.8M 1.56%
13 RXRX RECURSION PHARMACEUTICALS IN $2.2M 0.71%

Values as reported on the Q2 2026 Form 13F. Every position is in the holdings table below.

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