GREAT POINT PARTNERS LLC
Q2 2026 Form 13-F

GREENWICH, CONNECTICUT
CIK 0001281446 · CRD 158423 · SEC-registered investment adviser
Consolidated report · includes 2 managers since Q3 2013
$529.1M Reported Value Total

GREAT POINT PARTNERS, LLC reports 17 total accounts under management (AUM). There are 17 discretionary accounts valued at $1,777,101,406, and 0 non-discretionary accounts.

Source: Form ADV filed * Note that certain holdings are exempt from Form 13-F reporting, so the AUM totals may be greater than the Form 13-F total.
SEC Registered Discretionary Manager
Private funds (Form ADV)
38 funds · $2.0B gross asset value
Private Equity Fund: $1.4B · Hedge Fund: $564.4M
Source: Form ADV filed 2026-03-31
Reported value
$529.1M
Quarter over quarter
+16.1%
Holdings
37
Top-10 concentration
51.6%

Filing Structure

Reports holdings for

  • JAY JEFFREY R · File #028-12517 · since Q3 2013
  • Nordahl Lillian (not a 13F filer in our records) · File #028-24470 · since Q3 2024
  • Yehudai Ortav · File #028-20398 · Q3 2020 – Q2 2024
  • KROIN DAVID (not a 13F filer in our records) · File #028-13262 · Q3 2013 – Q2 2020

Holdings reported by

Key People

Form ADV owners & control persons
Jeffrey Robert Jay
ELECTED MANAGER, MEMBER AND MANAGING DIRECTOR
Adam Brian Felsenthal
GENERAL COUNSEL AND CHIEF COMPLIANCE OFFICER
Ronald Marc Panzier
CHIEF OPERATING OFFICER AND CHIEF FINANCIAL OFFICER

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Q2 2026 13F record

Q2 2026 13F filing summary

Q2 2026 Form 13F portfolio summary
Period of report June 30, 2026
Filed August 14, 2026
Form 13F-HR
Reported value $529.1M
Positions 37
Change in reported value +21.6%
New positions 11
Exited positions 13
Position turnover 48.0%
Top-10 concentration 51.6%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 14, 2026
37 $529.1M
Q1 2026 13F
Filed May 15, 2026
39 $435.1M
Q4 2025 13F
Filed Feb 17, 2026
29 $308.4M
Q3 2025 13F
Filed Nov 14, 2025
28 $242.5M
Q2 2025 13F
Filed Aug 14, 2025
26 $153.8M
Q1 2025 13F
Filed May 15, 2025
31 $188.8M
Q4 2024 13F
Filed Feb 14, 2025
26 $212.2M
Q3 2024 13F
Filed Nov 13, 2024
29 $339.8M
Q2 2024 13F
Filed Aug 14, 2024
33 $522.0M
Q1 2024 13F
Filed May 15, 2024
35 $641.6M
Q4 2023 13F
Filed Feb 14, 2024
34 $586.7M
Q3 2023 13F
Filed Nov 14, 2023
39 $549.0M
Q2 2023 13F
Filed Aug 14, 2023
36 $510.8M
Q1 2023 13F
Filed May 15, 2023
42 $509.3M
Q4 2022 13F
Filed Feb 14, 2023
40 $510.2M
Q3 2022 13F
Filed Nov 14, 2022
40 $415.3M
Q2 2022 13F
Filed Aug 15, 2022
33 $417.0M
Q1 2022 13F
Filed May 16, 2022
29 $413.8M
Q4 2021 13F
Filed Feb 14, 2022
35 $450.1M
Q3 2021 13F
Filed Nov 15, 2021
35 $429.5M

32 earlier quarters on file — choose one from the quarter menu above.

Top 20 holdings · Q2 2026

Largest Q2 2026 13F positions by reported value
# Holding Reported value % of portfolio
1 ABVX C ABIVAX SA $53.3M 10.07%
2 VOR VOR BIOPHARMA INC $31.3M 5.91%
3 ABVX ABIVAX SA $27.2M 5.15%
4 IBRX P IMMUNITYBIO INC $26.3M 4.97%
5 VERA VERA THERAPEUTICS INC $25.8M 4.87%
6 ZURA ZURA BIO LTD $24.9M 4.7%
7 ALMS ALUMIS INC $24.1M 4.55%
8 SLGL SOL-GEL TECHNOLOGIES LTD $20.3M 3.84%
9 RARE P ULTRAGENYX PHARMACEUTICAL IN $20.0M 3.79%
10 DFTX DEFINIUM THERAPEUTICS INC $20.0M 3.78%
11 ANNX ANNEXON INC $20.0M 3.78%
12 ORKA ORUKA THERAPEUTICS INC $17.4M 3.3%
13 MLTX MOONLAKE IMMUNOTHERAPEUTICS $16.7M 3.15%
14 SGMT SAGIMET BIOSCIENCES INC $15.7M 2.97%
15 CTNM CONTINEUM THERAPEUTICS INC $15.1M 2.85%
16 IMMX IMMIX BIOPHARMA INC $13.2M 2.49%
17 ELYM CLIMB BIO INC $13.0M 2.46%
18 AMLX AMYLYX PHARMACEUTICALS INC $12.6M 2.38%
19 NKTR NEKTAR THERAPEUTICS $12.2M 2.31%
20 NGNE NEUROGENE INC $11.1M 2.09%

Values as reported on the Q2 2026 Form 13F. Every position is in the holdings table below.

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