Vivo Capital LLC's Q4 2024 13F: 3 new positions, 6 exits

Form 13F-HR for the quarter ended Dec 31, 2024 · filed Feb 13, 2025 · 40 reported positions · accession 0001213900-25-013306

What changed this quarter

Vivo Capital LLC's changes in reported equity positions, Q4 2024
Activity Security Weight before Weight now Change Shares Shares %
Exited Harmony Biosciences Holdings Inc (HRMY) 8.6% — −8.6 pts −2.61M sh −100%
Reduced Verona Pharma PLC (VRNA) 8.5% 11.9% +3.4 pts −1.27M sh −36%
Exited Sinovac Biotech Ltd. (SVA) 6.3% — −6.3 pts −11.8M sh −100%
New Aclaris Therapeutics, Inc. (ACRS) — 2.5% +2.5 pts +8.89M sh new
New Cidara Therapeutics, Inc. (CDTX) — 2.0% +2.0 pts +671K sh new
Reduced Viridian Therapeutics Inc (VRDN) 3.2% 2.1% −1.0 pts −696K sh −41%
New Bright Minds Biosciences Inc (DRUG) — 1.0% +1.0 pts +252K sh new
Increased Delcath Systems, Inc. (DCTH) 0.7% 2.3% +1.6 pts +712K sh +71%
Increased Trevi Therapeutics Inc (TRVI) 0.4% 1.6% +1.2 pts +1.88M sh +116%
Exited ALX Oncology Holdings Inc (ALXO) 0.6% — −0.6 pts −4.03M sh −100%
Increased Unicycive Therapeutics (UNCY) 0.2% 0.9% +0.7 pts +5.5M sh +123%
Exited Adverum Biotechnologies, Inc. (ADVM) 0.5% — −0.5 pts −833K sh −100%
Increased Corvus Pharmaceuticals Holdings (CRVS) 0.7% 1.3% +0.7 pts +737K sh +49%
Exited Engene Holdings Inc. (ENGN) 0.4% — −0.4 pts −679K sh −100%
Exited Codexis, Inc (CDXS) 0.1% — −0.1 pts −388K sh −100%
Reduced Instil Bio Inc (TIL) 3.5% 1.3% −2.2 pts −38,854 sh −6%

Reported by the fund in its Form 13F filed with the SEC; holdings are as of the quarter-end report date and may have changed since. For informational purposes only — not investment advice or a recommendation to buy or sell any security. FilingExplorer is not affiliated with or endorsed by this fund. How this brief is compiled

† Security identifier (CUSIP) changed — read as one continuing position, not an exit and a new position:

  • DBV Technologies SA (DBVT): 23306J200 → 23306J309, 1.35M → 32,020 shares (share count changed with the identifier; not shown as a trade)

Top 10 positions — 73.7% of the equity book

Changes in the top 10 this quarter: ACRS entered · DCTH entered · CDTX entered · HRMY left · SVA left · TIL left

# Security Weight before Weight now
1 Soleno Therapeutics Inc (SLNO) 26.3% 31.7%
2 Verona Pharma PLC (VRNA) 8.5% 11.9%
3 Geron Corp (GERN) 10.2% 10.8%
4 Terns Pharmaceuticals Inc (TERN) 4.8% 4.3%
5 Avadel Pharmaceuticals PLC (AVDL) 2.9% 3.2%
6 Dyne Therapeutics Inc (DYN) 3.3% 2.9%
7 Aclaris Therapeutics, Inc. (ACRS) 0.0% 2.5% Entered the top 10
8 Delcath Systems, Inc. (DCTH) 0.7% 2.3% Entered the top 10
9 Viridian Therapeutics Inc (VRDN) 3.2% 2.1%
10 Cidara Therapeutics, Inc. (CDTX) 0.0% 2.0% Entered the top 10
— Harmony Biosciences Holdings Inc (HRMY) 8.6% 0.0% Left the top 10
— Sinovac Biotech Ltd. (SVA) 6.3% 0.0% Left the top 10
— Instil Bio Inc (TIL) 3.5% 1.3% Left the top 10

Weights are each position's reported value as a share of the fund's reported equity positions (options and principal-amount holdings excluded).