Vivo Capital LLC's Q1 2024 13F: 4 new positions, 9 exits

Form 13F-HR for the quarter ended Mar 31, 2024 · filed Apr 22, 2024 · 42 reported positions · accession 0001213900-24-034979

What changed this quarter

Vivo Capital LLC's changes in reported equity positions, Q1 2024
Activity Security Weight before Weight now Change Shares Shares %
Exited Gracell Biotechnologies Inc (GRCL) 7.8% — −7.8 pts −9.55M sh −100%
New Sinovac Biotech Ltd. (SVA) — 6.0% +6.0 pts +11.8M sh new
Reduced Tarsus Pharmaceuticals Inc (TARS) 3.0% 1.6% −1.3 pts −1.22M sh −68%
Exited Icosavax, Inc. (ICVX) 2.2% — −2.2 pts −1.7M sh −100%
New Adverum Biotechnologies, Inc. (ADVM) — 1.7% +1.7 pts +1.5M sh new
Increased Dyne Therapeutics Inc (DYN) 1.1% 3.6% +2.5 pts +600K sh +58%
New Regulus Therapeutics Inc (RGLS) — 1.1% +1.1 pts +5M sh new
Increased Silence Therapeutics PLC (SLN) 0.7% 1.9% +1.2 pts +595K sh +117%
Reduced Alpine Immune Sciences Inc (ALPN) 1.3% 1.6% +0.4 pts −299K sh −36%
Exited Apogee Therapeutics Inc (APGE) 0.9% — −0.9 pts −400K sh −100%
Exited KalVista Pharmaceuticals Inc. (KALV) 0.9% — −0.9 pts −856K sh −100%
Reduced Verona Pharma PLC (VRNA) 6.9% 4.6% −2.4 pts −640K sh −15%
Increased Geron Corp (GERN) 4.2% 7.1% +2.9 pts +3.08M sh +13%
Exited Pharvaris NV (PHVS) 0.7% — −0.7 pts −285K sh −100%
Exited Rayzebio Inc (RYZB) 0.6% — −0.6 pts −111K sh −100%
New Q32 Bio Inc. (QTTB) — 0.5% +0.5 pts +370K sh new
Exited Iovance Biotherapeutics Inc (IOVA) 0.4% — −0.4 pts −655K sh −100%
Exited Arrowhead Pharmaceuticals Inc (ARWR) 0.3% — −0.3 pts −137K sh −100%
Increased Delcath Systems, Inc. (DCTH) 0.3% 0.6% +0.3 pts +812K sh +95%
Reduced Astria Therapeutics Inc (ATXS) 1.6% 2.6% +1.0 pts −154K sh −6%
Reduced Avadel Pharmaceuticals PLC (AVDL) 4.7% 5.3% +0.5 pts −124K sh −3%
Increased Zai Lab Ltd (ZLAB) 0.9% 0.7% −0.3 pts +120K sh +29%
Reduced Rezolute Inc (RZLT) 0.3% 0.6% +0.3 pts −445K sh −14%
Exited Homology Medicines, Inc. (FIXX) 0.0% — 0.0 pts −370K sh −100%
Reduced Instil Bio Inc (TIL) 0.4% 0.5% +0.1 pts −2 sh 0%

Reported by the fund in its Form 13F filed with the SEC; holdings are as of the quarter-end report date and may have changed since. For informational purposes only — not investment advice or a recommendation to buy or sell any security. FilingExplorer is not affiliated with or endorsed by this fund. How this brief is compiled

† Security identifier (CUSIP) changed — read as one continuing position, not an exit and a new position:

  • Precision Biosciences Inc (DTIL): 74019P108 → 74019P207, 140K → 4,675 shares (share count change consistent with a stock split)

Top 10 positions — 71.4% of the equity book

Changes in the top 10 this quarter: SVA entered · DYN entered · ATXS entered · GRCL left · VRDN left · TARS left

# Security Weight before Weight now
1 Soleno Therapeutics Inc (SLNO) 27.7% 28.3%
2 Geron Corp (GERN) 4.2% 7.1%
3 Harmony Biosciences Holdings Inc (HRMY) 6.9% 6.9%
4 Sinovac Biotech Ltd. (SVA) 0.0% 6.0% Entered the top 10
5 Avadel Pharmaceuticals PLC (AVDL) 4.7% 5.3%
6 Verona Pharma PLC (VRNA) 6.9% 4.6%
7 ALX Oncology Holdings Inc (ALXO) 5.1% 3.7%
8 Dyne Therapeutics Inc (DYN) 1.1% 3.6% Entered the top 10
9 Terns Pharmaceuticals Inc (TERN) 3.5% 3.4%
10 Astria Therapeutics Inc (ATXS) 1.6% 2.6% Entered the top 10
— Gracell Biotechnologies Inc (GRCL) 7.8% 0.0% Left the top 10
— Viridian Therapeutics Inc (VRDN) 3.0% 2.3% Left the top 10
— Tarsus Pharmaceuticals Inc (TARS) 3.0% 1.6% Left the top 10

Weights are each position's reported value as a share of the fund's reported equity positions (options and principal-amount holdings excluded).