STEMPOINT CAPITAL LP's Q2 2026 13F: 25 new positions, 22 exits
Form 13F-HR for the quarter ended Jun 30, 2026 · filed Aug 14, 2026 · 73 reported positions · accession 0001420506-26-001687
What changed this quarter
| Activity | Security | Weight before | Weight now | Change | Shares | Shares % |
|---|---|---|---|---|---|---|
| Reduced | SCHOLAR ROCK HLDG CORP (SRRK) | 9.8% | 2.3% | −7.5 pts | −796K sh | −77% |
| Increased | TANGO THERAPEUTICS INC (TNGX) | 0.8% | 6.6% | +5.8 pts | +1.02M sh | +509% |
| Exited | SYNDAX PHARMACEUTICALS INC (SNDX) | 5.5% | — | −5.5 pts | −1.22M sh | −100% |
| Increased | ERASCA INC (ERAS) | 0.7% | 5.0% | +4.2 pts | +1.33M sh | +553% |
| Reduced | REVOLUTION MEDICINES INC (RVMD) | 5.3% | 5.2% | −0.1 pts | −122K sh | −43% |
| Reduced | IMMUNOVANT INC (IMVT) | 3.6% | 1.8% | −1.7 pts | −470K sh | −63% |
| Exited | MBX BIOSCIENCES INC (MBX) | 2.9% | — | −2.9 pts | −499K sh | −100% |
| Increased | TYRA BIOSCIENCES INC (TYRA) | 1.4% | 3.5% | +2.1 pts | +440K sh | +228% |
| New | KINIKSA PHARMACEUTICALS INTL (KNSA) | — | 2.3% | +2.3 pts | +209K sh | new |
| New | FIRST TRACKS BIOTHERAPEUTICS (TRAX) | — | 2.2% | +2.2 pts | +623K sh | new |
| Increased | DIANTHUS THERAPEUTICS INC (DNTH) | 1.4% | 3.4% | +2.0 pts | +115K sh | +135% |
| New | ORUKA THERAPEUTICS INC (ORKA) | — | 1.9% | +1.9 pts | +116K sh | new |
| Exited | DYNE THERAPEUTICS INC (DYN) | 1.8% | — | −1.8 pts | −506K sh | −100% |
| Exited | EDGEWISE THERAPEUTICS INC (EWTX) | 1.8% | — | −1.8 pts | −291K sh | −100% |
| New | CLIMB BIO INC (ELYM) | — | 1.7% | +1.7 pts | +743K sh | new |
| Exited | DENALI THERAPEUTICS INC (DNLI) | 1.6% | — | −1.6 pts | −427K sh | −100% |
| Reduced | DEFINIUM THERAPEUTICS INC (DFTX) | 1.2% | 1.1% | −0.1 pts | −188K sh | −58% |
| Increased | ALKERMES PLC (ALKS) | 0.5% | 2.2% | +1.7 pts | +168K sh | +208% |
| Reduced | STRUCTURE THERAPEUTICS INC (GPCR) | 1.9% | 0.4% | −1.5 pts | −162K sh | −81% |
| Reduced | ARCUTIS BIOTHERAPEUTICS INC (ARQT) | 1.9% | 0.4% | −1.4 pts | −315K sh | −76% |
| Reduced | BIOHAVEN LTD (BHVN) | 2.6% | 2.7% | +0.1 pts | −530K sh | −33% |
| New | INFLARX NV (IFRX) | — | 1.3% | +1.3 pts | +3.23M sh | new |
| Reduced | PROTAGONIST THERAPEUTICS INC (PTGX) | 1.5% | 0.3% | −1.1 pts | −56,274 sh | −78% |
| Reduced | EYEPOINT INC (EYPT) | 2.0% | 0.8% | −1.2 pts | −472K sh | −58% |
| New | OVID THERAPEUTICS INC (OVID) | — | 1.1% | +1.1 pts | +2.42M sh | new |
| New | EQUILLIUM INC (EQ) | — | 1.1% | +1.1 pts | +2.02M sh | new |
| Reduced | PRAXIS PRECISION MEDICINES I (PRAX) | 3.5% | 2.2% | −1.3 pts | −19,024 sh | −34% |
| Increased | RELMADA THERAPEUTICS INC (RLMD) | 0.8% | 1.7% | +0.9 pts | +863K sh | +144% |
| New | DAMORA THERAPEUTICS INC (GLTO) | — | 1.0% | +1.0 pts | +216K sh | new |
| Exited | NURIX THERAPEUTICS INC (NRIX) | 0.9% | — | −0.9 pts | −315K sh | −100% |
| New | INVENTIVA SA (IVA) | — | 0.9% | +0.9 pts | +1.43M sh | new |
| Reduced | SPYRE THERAPEUTICS INC (SYRE) | 1.6% | 1.6% | 0.0 pts | −60,680 sh | −36% |
| New | CENTURY THERAPEUTICS INC (IPSC) | — | 0.9% | +0.9 pts | +2.15M sh | new |
| Reduced | AMYLYX PHARMACEUTICALS INC (AMLX) | 1.8% | 1.2% | −0.6 pts | −285K sh | −43% |
| New | AURA BIOSCIENCES INC (AURA) | — | 0.9% | +0.9 pts | +714K sh | new |
| Exited | EVOMMUNE INC (EVMN) | 0.8% | — | −0.8 pts | −194K sh | −100% |
| Exited | SENSEI BIOTHERAPEUTICS INC (SNSE) | 0.8% | — | −0.8 pts | −133K sh | −100% |
| Reduced | CYTOKINETICS INC (CYTK) | 1.6% | 1.1% | −0.5 pts | −53,974 sh | −42% |
| Exited | JOHNSON & JOHNSON (JNJ) | 0.7% | — | −0.7 pts | −15,415 sh | −100% |
| New | COMPASS PATHWAYS PLC (CMPS) | — | 0.7% | +0.7 pts | +285K sh | new |
| Reduced | ABIVAX SA (ABVX) | 6.7% | 6.5% | −0.2 pts | −30,134 sh | −10% |
| Increased | CELCUITY INC (CELC) | 1.3% | 1.8% | +0.5 pts | +38,141 sh | +64% |
| Reduced | XENON PHARMACEUTICALS INC (XENE) | 1.6% | 0.8% | −0.8 pts | −64,680 sh | −46% |
| Exited | X4 PHARMACEUTICALS INC (XFOR) | 0.7% | — | −0.7 pts | −851K sh | −100% |
| New | AVALYN PHARMACEUTICALS INC (AVLN) | — | 0.7% | +0.7 pts | +118K sh | new |
| Exited | VAXCYTE INC (PCVX) | 0.7% | — | −0.7 pts | −59,061 sh | −100% |
| New | AXSOME THERAPEUTICS INC. (AXSM) | — | 0.7% | +0.7 pts | +15,375 sh | new |
| New | MONTE ROSA THERAPEUTICS INC (GLUE) | — | 0.6% | +0.6 pts | +154K sh | new |
| Increased | ZURA BIO LTD (ZURA) | 0.9% | 1.4% | +0.5 pts | +615K sh | +82% |
| Reduced | NEWAMSTERDAM PHARMA COMPANY (NAMS) | 1.1% | 0.5% | −0.7 pts | −103K sh | −57% |
The 50 largest of 94 changes, by size of the trade. Full holdings for this quarter.
Reported by the fund in its Form 13F filed with the SEC; holdings are as of the quarter-end report date and may have changed since. For informational purposes only — not investment advice or a recommendation to buy or sell any security. FilingExplorer is not affiliated with or endorsed by this fund. How this brief is compiled
Top 10 positions — 41.2% of the equity book
Changes in the top 10 this quarter: TNGX entered · ERAS entered · TYRA entered · DNTH entered · BHVN entered · SRZN entered · SRRK left · SNDX left · IMVT left · PRAX left · MBX left · CGON left
| # | Security | Weight before | Weight now | |
|---|---|---|---|---|
| 1 | TANGO THERAPEUTICS INC (TNGX) | 0.8% | 6.6% | Entered the top 10 |
| 2 | ABIVAX SA (ABVX) | 6.7% | 6.5% | |
| 3 | REVOLUTION MEDICINES INC (RVMD) | 5.3% | 5.2% | |
| 4 | ERASCA INC (ERAS) | 0.7% | 5.0% | Entered the top 10 |
| 5 | TYRA BIOSCIENCES INC (TYRA) | 1.4% | 3.5% | Entered the top 10 |
| 6 | DIANTHUS THERAPEUTICS INC (DNTH) | 1.4% | 3.4% | Entered the top 10 |
| 7 | ENLIVEN THERAPEUTICS INC (ELVN) | 2.7% | 3.0% | |
| 8 | MINERALYS THERAPEUTICS INC (MLYS) | 2.8% | 2.8% | |
| 9 | BIOHAVEN LTD (BHVN) | 2.6% | 2.7% | Entered the top 10 |
| 10 | SURROZEN INC (SRZN) | 2.6% | 2.4% | Entered the top 10 |
| — | SCHOLAR ROCK HLDG CORP (SRRK) | 9.8% | 2.3% | Left the top 10 |
| — | SYNDAX PHARMACEUTICALS INC (SNDX) | 5.5% | 0.0% | Left the top 10 |
| — | IMMUNOVANT INC (IMVT) | 3.6% | 1.8% | Left the top 10 |
| — | PRAXIS PRECISION MEDICINES I (PRAX) | 3.5% | 2.2% | Left the top 10 |
| — | MBX BIOSCIENCES INC (MBX) | 2.9% | 0.0% | Left the top 10 |
| — | CG ONCOLOGY INC (CGON) | 2.7% | 2.0% | Left the top 10 |
Weights are each position's reported value as a share of the fund's reported equity positions (options and principal-amount holdings excluded).
Option positions (puts and calls)
Reported separately from the positions above. The value a 13F reports for an option is that of the underlying shares, not the option itself.
| Activity | Security | Type | Shares before | Shares now | Reported value |
|---|---|---|---|---|---|
| New | PERSONALIS INC (PSNL) | Call | 0 | 470K | $811K |
| Exited | SCHOLAR ROCK HLDG CORP (SRRK) | Call | 100K | 0 | $0 |
| New | BIOHAVEN LTD (BHVN) | Call | 0 | 500K | $525K |
| New | SPDR SERIES TRUST (XBI) | Put | 0 | 250K | $400K |
| Reduced | REVOLUTION MEDICINES INC (RVMD) | Put | 100K | 30,000 | $128K |
| Exited | TYRA BIOSCIENCES INC (TYRA) | Call | 100K | 0 | $0 |
| Exited | IMMUNOVANT INC (IMVT) | Call | 100K | 0 | $0 |
| New | ASTRAZENECA PLC (AZN) | Call | 0 | 25,000 | $180K |
| New | TANGO THERAPEUTICS INC (TNGX) | Call | 0 | 100K | $175K |
| New | ERASCA INC (ERAS) | Put | 0 | 200K | $90K |
| Exited | SYNDAX PHARMACEUTICALS INC (SNDX) | Call | 150K | 0 | $0 |
| Exited | STATE STR SPDR S&P 500 ETF T (SPY) | Call | 50,000 | 0 | $0 |
| New | ARK ETF TR (ARKG) | Put | 0 | 100K | $75K |
| Exited | INVESCO QQQ TR (QQQ) | Call | 40,000 | 0 | $0 |
| New | ROIVANT SCIENCES LTD (ROIV) | Put | 0 | 100K | $40K |
| New | AMGEN INC (AMGN) | Put | 0 | 15,000 | $15K |
| Increased | SPDR SERIES TRUST (XBI) | Call | 150K | 400K | $178K |
| Exited | BOSTON SCIENTIFIC CORP (BSX) | Call | 250K | 0 | $0 |
| Exited | TERNS PHARMACEUTICALS INC (TERN) | Call | 100K | 0 | $0 |
| Exited | OLEMA PHARMACEUTICALS INC (OLMA) | Call | 25,000 | 0 | $0 |
| Exited | EDWARDS LIFESCIENCES CORP (EW) | Call | 10,000 | 0 | $0 |