STEMPOINT CAPITAL LP's Q3 2024 13F: 21 new positions, 13 exits
Form 13F-HR for the quarter ended Sep 30, 2024 · filed Nov 13, 2024 · 50 reported positions · accession 0001420506-24-002386
What changed this quarter
| Activity | Security | Weight before | Weight now | Change | Shares | Shares % |
|---|---|---|---|---|---|---|
| Reduced | ARCELLX INC (ACLX) | 4.6% | 1.5% | −3.1 pts | −221K sh | −79% |
| Reduced | CRINETICS PHARMACEUTICALS IN (CRNX) | 7.3% | 3.3% | −4.0 pts | −337K sh | −61% |
| New | BRISTOL-MYERS SQUIBB CO (BMY) | — | 4.3% | +4.3 pts | +275K sh | new |
| Exited | IMMUNOCORE HLDGS PLC (IMCR) | 3.4% | — | −3.4 pts | −339K sh | −100% |
| Exited | MERCK & CO INC (MRK) | 3.0% | — | −3.0 pts | −81,508 sh | −100% |
| Reduced | IMMUNOVANT INC (IMVT) | 7.9% | 5.7% | −2.1 pts | −341K sh | −34% |
| Exited | GSK PLC (GSK) | 2.8% | — | −2.8 pts | −246K sh | −100% |
| New | INCYTE CORP (INCY) | — | 2.6% | +2.6 pts | +129K sh | new |
| Exited | KALVISTA PHARMACEUTICALS INC (KALV) | 2.6% | — | −2.6 pts | −737K sh | −100% |
| Increased | PRAXIS PRECISION MEDICINES I (PRAX) | 0.4% | 3.0% | +2.6 pts | +145K sh | +495% |
| Increased | ARCUTIS BIOTHERAPEUTICS INC (ARQT) | 2.6% | 5.0% | +2.3 pts | +813K sh | +84% |
| New | DAY ONE BIOPHARMACEUTICALS I (DAWN) | — | 2.1% | +2.1 pts | +507K sh | new |
| Reduced | EDGEWISE THERAPEUTICS INC (EWTX) | 1.4% | 0.2% | −1.3 pts | −251K sh | −93% |
| Increased | MERUS N V (MRUS) | 5.0% | 6.3% | +1.3 pts | +133K sh | +46% |
| New | ACELYRIN INC (SLRN) | — | 1.9% | +1.9 pts | +1.32M sh | new |
| New | SOLENO THERAPEUTICS INC (SLNO) | — | 1.9% | +1.9 pts | +123K sh | new |
| Increased | SYNDAX PHARMACEUTICALS INC (SNDX) | 8.5% | 10.0% | +1.5 pts | +319K sh | +23% |
| Exited | INSMED INC (INSM) | 1.7% | — | −1.7 pts | −86,980 sh | −100% |
| Reduced | APPLIED THERAPEUTICS INC (APLT) | 3.0% | 4.0% | +0.9 pts | −657K sh | −30% |
| Exited | CELLDEX THERAPEUTICS INC NEW (CLDX) | 1.6% | — | −1.6 pts | −144K sh | −100% |
| New | KEROS THERAPEUTICS INC (KROS) | — | 1.5% | +1.5 pts | +86,930 sh | new |
| Exited | LARIMAR THERAPEUTICS INC (LRMR) | 1.5% | — | −1.5 pts | −704K sh | −100% |
| Exited | CORBUS PHARMACEUTICALS HLDGS (CRBP) | 1.4% | — | −1.4 pts | −101K sh | −100% |
| New | ZURA BIO LTD (ZURA) | — | 1.3% | +1.3 pts | +1.04M sh | new |
| Exited | FULCRUM THERAPEUTICS INC (FULC) | 1.3% | — | −1.3 pts | −696K sh | −100% |
| New | TERNS PHARMACEUTICALS INC (TERN) | — | 1.1% | +1.1 pts | +449K sh | new |
| Exited | SPYRE THERAPEUTICS INC (SYRE) | 1.0% | — | −1.0 pts | −150K sh | −100% |
| Exited | JASPER THERAPEUTICS INC (JSPR) | 1.0% | — | −1.0 pts | −144K sh | −100% |
| Exited | BLACK DIAMOND THERAPEUTICS I (BDTX) | 0.9% | — | −0.9 pts | −674K sh | −100% |
| New | UROGEN PHARMA LTD (URGN) | — | 0.9% | +0.9 pts | +242K sh | new |
| New | WAVE LIFE SCIENCES LTD (WVE) | — | 0.7% | +0.7 pts | +300K sh | new |
| New | BRIDGEBIO PHARMA INC (BBIO) | — | 0.7% | +0.7 pts | +94,885 sh | new |
| Exited | SILENCE THERAPEUTICS PLC (SLN) | 0.7% | — | −0.7 pts | −125K sh | −100% |
| New | RHYTHM PHARMACEUTICALS INC (RYTM) | — | 0.6% | +0.6 pts | +41,268 sh | new |
| Reduced | JANUX THERAPEUTICS INC (JANX) | 1.1% | 0.7% | −0.5 pts | −43,534 sh | −47% |
| New | SAREPTA THERAPEUTICS INC (SRPT) | — | 0.6% | +0.6 pts | +15,014 sh | new |
| New | TOURMALINE BIO INC (TRML) | — | 0.4% | +0.4 pts | +55,523 sh | new |
| New | CAPRICOR THERAPEUTICS INC (CAPR) | — | 0.4% | +0.4 pts | +93,638 sh | new |
| Reduced | PERSPECTIVE THERAPEUTICS INC (CATX) | 1.0% | 1.0% | −0.1 pts | −106K sh | −31% |
| New | ALKERMES PLC (ALKS) | — | 0.4% | +0.4 pts | +48,918 sh | new |
| New | CENTESSA PHARMACEUTICALS PLC (CNTA) | — | 0.4% | +0.4 pts | +83,662 sh | new |
| New | MBX BIOSCIENCES INC (MBX) | — | 0.4% | +0.4 pts | +50,000 sh | new |
| Reduced | PYXIS ONCOLOGY INC (PYXS) | 1.2% | 0.9% | −0.2 pts | −352K sh | −29% |
| Increased | IDEAYA BIOSCIENCES INC (IDYA) | 1.1% | 1.3% | +0.2 pts | +30,916 sh | +30% |
| Increased | DENALI THERAPEUTICS INC (DNLI) | 1.7% | 2.5% | +0.7 pts | +31,040 sh | +12% |
| Reduced | BIOHAVEN LTD (BHVN) | 2.4% | 3.2% | +0.9 pts | −16,815 sh | −7% |
| New | CYTOKINETICS INC (CYTK) | — | 0.2% | +0.2 pts | +14,464 sh | new |
| New | REVOLUTION MEDICINES INC (RVMD) | — | 0.2% | +0.2 pts | +16,654 sh | new |
| Increased | ROIVANT SCIENCES LTD (ROIV) | 8.4% | 9.6% | +1.2 pts | +57,078 sh | +2% |
| New | ASTRIA THERAPEUTICS INC (ATXS) | — | 0.2% | +0.2 pts | +56,287 sh | new |
The 50 largest of 61 changes, by size of the trade. Full holdings for this quarter.
Reported by the fund in its Form 13F filed with the SEC; holdings are as of the quarter-end report date and may have changed since. For informational purposes only — not investment advice or a recommendation to buy or sell any security. FilingExplorer is not affiliated with or endorsed by this fund. How this brief is compiled
Top 10 positions — 56.1% of the equity book
Changes in the top 10 this quarter: ARQT entered · BMY entered · BHVN entered · ACLX left · IMCR left · MRK left
| # | Security | Weight before | Weight now | |
|---|---|---|---|---|
| 1 | SYNDAX PHARMACEUTICALS INC (SNDX) | 8.5% | 10.0% | |
| 2 | ROIVANT SCIENCES LTD (ROIV) | 8.4% | 9.6% | |
| 3 | MERUS N V (MRUS) | 5.0% | 6.3% | |
| 4 | IMMUNOVANT INC (IMVT) | 7.9% | 5.7% | |
| 5 | ARCUTIS BIOTHERAPEUTICS INC (ARQT) | 2.6% | 5.0% | Entered the top 10 |
| 6 | AMICUS THERAPEUTICS INC (FOLD) | 4.4% | 4.7% | |
| 7 | BRISTOL-MYERS SQUIBB CO (BMY) | 0.0% | 4.3% | Entered the top 10 |
| 8 | APPLIED THERAPEUTICS INC (APLT) | 3.0% | 4.0% | |
| 9 | CRINETICS PHARMACEUTICALS IN (CRNX) | 7.3% | 3.3% | |
| 10 | BIOHAVEN LTD (BHVN) | 2.4% | 3.2% | Entered the top 10 |
| — | ARCELLX INC (ACLX) | 4.6% | 1.5% | Left the top 10 |
| — | IMMUNOCORE HLDGS PLC (IMCR) | 3.4% | 0.0% | Left the top 10 |
| — | MERCK & CO INC (MRK) | 3.0% | 0.0% | Left the top 10 |
Weights are each position's reported value as a share of the fund's reported equity positions (options and principal-amount holdings excluded).
Option positions (puts and calls)
Reported separately from the positions above. The value a 13F reports for an option is that of the underlying shares, not the option itself.
| Activity | Security | Type | Shares before | Shares now | Reported value |
|---|---|---|---|---|---|
| New | SYNDAX PHARMACEUTICALS INC (SNDX) | Call | 0 | 230K | $382K |
| Reduced | ARCUTIS BIOTHERAPEUTICS INC (ARQT) | Call | 500K | 250K | $12.5K |
| New | IMMUNOVANT INC (IMVT) | Call | 0 | 200K | $113K |
| New | APPLIED THERAPEUTICS INC (APLT) | Call | 0 | 252K | $75.5K |