SOLEUS CAPITAL MANAGEMENT L P
Q3 2025 Form 13-F

GREENWICH, CONNECTICUT
CIK 0001802630 · CRD 294459 · SEC-registered investment adviser
$2.0B Reported Value Total

SOLEUS CAPITAL MANAGEMENT, L.P. reports 14 total accounts under management (AUM). There are 14 discretionary accounts valued at $2,335,377,666, and 0 non-discretionary accounts.

Source: Form ADV filed * Note that certain holdings are exempt from Form 13-F reporting, so the AUM totals may be greater than the Form 13-F total.
SEC Registered Discretionary Manager
Private funds (Form ADV)
14 funds · $3.8B gross asset value
Hedge Fund: $3.0B · Private Equity Fund: $765.8M
Source: Form ADV filed 2026-04-27
Reported value
$2.0B
Quarter over quarter
+26.8%
Holdings
87
Top-10 concentration
48.1%

Key People

Form ADV owners & control persons
Guy Bezalel Levy
SOLE OWNER
Charles Arthur Davis
MEMBER
Stephen Nmn Friedman
MEMBER

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Q3 2025 13F record

Q3 2025 13F filing summary

Q3 2025 Form 13F portfolio summary
Period of report September 30, 2025
Filed November 14, 2025
Form 13F-HR
Reported value $2.0B
Positions 87
Change in reported value +31.5%
New positions 18
Exited positions 25
Position turnover 38.4%
Top-10 concentration 48.1%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 11, 2026
97 $2.9B
Q1 2026 13F
Filed May 14, 2026
93 $2.5B
Q4 2025 13F
Filed Feb 12, 2026
94 $2.7B
Q3 2025 13F
Filed Nov 14, 2025
87 $2.0B
Q2 2025 13F
Filed Aug 15, 2025
94 $1.5B
Q1 2025 13F
Filed May 15, 2025
74 $1.4B
Q4 2024 13F
Filed Feb 14, 2025
80 $1.6B
Q3 2024 13F
Filed Nov 14, 2024
86 $1.3B
Q2 2024 13F
Filed Aug 14, 2024
92 $1.1B
Q1 2024 13F
Filed May 15, 2024
90 $1.3B
Q4 2023 13F
Filed Feb 14, 2024
73 $901.2M
Q3 2023 13F
Filed Nov 14, 2023
90 $1.1B
Q2 2023 13F
Filed Aug 14, 2023
101 $899.5M
Q1 2023 13F
Filed May 15, 2023
76 $965.7M
Q4 2022 13F
Filed Feb 14, 2023
72 $697.1M
Q3 2022 13F
Filed Nov 14, 2022
75 $736.0M
Q2 2022 13F
Filed Aug 15, 2022
70 $641.0M
Q1 2022 13F
Filed May 16, 2022
63 $775.1M
Q4 2021 13F
Filed Feb 14, 2022
65 $998.8M
Q3 2021 13F
Filed Nov 15, 2021
70 $641.7M

7 earlier quarters on file — choose one from the quarter menu above.

Top 20 holdings · Q3 2025

Largest Q3 2025 13F positions by reported value
# Holding Reported value % of portfolio
1 KRYS KRYSTAL BIOTECH INC $179.9M 9.05%
2 TGTX TG THERAPEUTICS INC $138.9M 6.99%
3 NVCR NOVOCURE LTD $124.6M 6.27%
4 XBI P SPDR SERIES TRUST $115.2M 5.8%
5 ELV ELEVANCE HEALTH INC FORMERLY $83.9M 4.22%
6 BBNX BETA BIONICS INC $76.9M 3.87%
7 UTHR UNITED THERAPEUTICS CORP DEL $62.9M 3.17%
8 TERN TERNS PHARMACEUTICALS INC $61.0M 3.07%
9 CELC CELCUITY INC $58.2M 2.93%
10 INSP INSPIRE MED SYS INC $54.0M 2.72%
11 TWST TWIST BIOSCIENCE CORP $52.5M 2.64%
12 ARGX ARGENX SE $51.2M 2.58%
13 ORGO ORGANOGENESIS HLDGS INC $51.2M 2.58%
14 BMRN BIOMARIN PHARMACEUTICAL INC $48.2M 2.43%
15 CDTX CIDARA THERAPEUTICS INC $47.3M 2.38%
16 PRAX PRAXIS PRECISION MEDICINES I $45.5M 2.29%
17 FOLD AMICUS THERAPEUTICS INC $37.0M 1.86%
18 INDV INDIVIOR PLC $35.3M 1.78%
19 MDGL MADRIGAL PHARMACEUTICALS INC $31.3M 1.58%
20 ANIP ANI PHARMACEUTICALS INC $31.2M 1.57%

Values as reported on the Q3 2025 Form 13F. Every position is in the holdings table below.

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