Redmile Group LLC's Q2 2022 13F: 4 new positions, 3 exits
Form 13F-HR for the quarter ended Jun 30, 2022 · filed Aug 15, 2022 · 71 reported positions · accession 0001104659-22-091334
What changed this quarter
| Activity | Security | Weight before | Weight now | Change | Shares | Shares % |
|---|---|---|---|---|---|---|
| Increased | SEAGEN INC (SGEN) | 2.0% | 5.8% | +3.8 pts | +413K sh | +94% |
| New | HORIZON THERAPEUTICS PUB L (HZNP) | — | 2.8% | +2.8 pts | +913K sh | new |
| New | XENON PHARMACEUTICALS INC (XENE) | — | 1.9% | +1.9 pts | +1.64M sh | new |
| Reduced | ARGENX SE (ARGX) | 5.1% | 5.6% | +0.5 pts | −130K sh | −25% |
| New | BIOMARIN PHARMACEUTICAL INC (BMRN) | — | 0.9% | +0.9 pts | +300K sh | new |
| Exited | UNITEDHEALTH GROUP INC (UNH) | 0.9% | — | −0.9 pts | −53,445 sh | −100% |
| Reduced | LIVANOVA PLC (LIVN) | 5.0% | 3.9% | −1.2 pts | −347K sh | −18% |
| Increased | MEDAVAIL HOLDINGS INC (MDVL) | 0.3% | 1.5% | +1.1 pts | +14.12M sh | +127% |
| Exited | ICU MED INC (ICUI) | 0.7% | — | −0.7 pts | −96,869 sh | −100% |
| Increased | DECIPHERA PHARMACEUTICALS IN (DCPH) | 0.2% | 0.7% | +0.5 pts | +766K sh | +115% |
| Increased | ZYMEWORKS INC | 0.4% | 0.8% | +0.3 pts | +1.72M sh | +81% |
| Increased | 1LIFE HEALTHCARE INC (ONEM) | 1.2% | 1.4% | +0.2 pts | +1.12M sh | +33% |
| Reduced | SOMALOGIC INC (SLGC) | 1.0% | 0.4% | −0.6 pts | −1.82M sh | −47% |
| New | PRIVIA HEALTH GROUP INC (PRVA) | — | 0.2% | +0.2 pts | +206K sh | new |
| Increased | SCHOLAR ROCK HLDG CORP (SRRK) | 1.0% | 0.7% | −0.3 pts | +997K sh | +41% |
| Increased | KRYSTAL BIOTECH INC (KRYS) | 3.8% | 4.8% | +1.0 pts | +82,847 sh | +5% |
| Reduced | TANDEM DIABETES CARE INC (TNDM) | 1.0% | 0.4% | −0.6 pts | −83,758 sh | −31% |
| Reduced | THE ONCOLOGY INSTITUTE INC (DFPH) | 0.5% | 0.3% | −0.2 pts | −678K sh | −28% |
| Reduced | JAZZ PHARMACEUTICALS PLC (JAZZ) | 0.6% | 0.6% | 0.0 pts | −21,500 sh | −19% |
| Increased | OAK STR HEALTH INC (OSH) | 1.0% | 0.9% | −0.1 pts | +180K sh | +15% |
| Reduced | IMMATICS N.V (IMTX) | 0.2% | 0.1% | 0.0 pts | −275K sh | −38% |
| Reduced | AMICUS THERAPEUTICS INC (FOLD) | 6.6% | 9.1% | +2.5 pts | −170K sh | −1% |
| Reduced | THE BEAUTY HEALTH COMPANY (SKIN) | 2.8% | 2.5% | −0.2 pts | −118K sh | −2% |
| Increased | RAPT THERAPEUTICS INC (RAPT) | 0.5% | 0.6% | +0.1 pts | +69,155 sh | +9% |
| Increased | ANNEXON INC (ANNX) | 0.3% | 0.5% | +0.2 pts | +300K sh | +9% |
| Reduced | REPLIMUNE GROUP INC (REPL) | 2.0% | 2.4% | +0.5 pts | −46,003 sh | −1% |
| Increased | REGENXBIO INC (RGNX) | 2.0% | 1.9% | −0.2 pts | +27,740 sh | +1% |
| Increased | CELLDEX THERAPEUTICS INC NEW (CLDX) | 2.2% | 2.1% | 0.0 pts | +24,019 sh | +1% |
| Increased | ADC THERAPEUTICS SA (ADCT) | 3.4% | 2.3% | −1.1 pts | +79,600 sh | +1% |
| Reduced | STEVANATO GROUP S P A (STVN) | 0.7% | 0.7% | 0.0 pts | −34,400 sh | −3% |
| Increased | BEAM THERAPEUTICS INC (BEAM) | 3.3% | 2.7% | −0.5 pts | +13,837 sh | +1% |
| Exited | EPIZYME INC (EPZM) | 0.0% | — | 0.0 pts | −454K sh | −100% |
| Reduced | STOKE THERAPEUTICS INC (STOK) | 1.3% | 1.0% | −0.3 pts | −31,100 sh | −2% |
| Increased | ELEVANCE HEALTH INC (ELV) | 1.3% | 1.5% | +0.3 pts | +825 sh | +1% |
| Reduced | IMMUNOGEN INC (IMGN) | 1.4% | 1.6% | +0.2 pts | −76,900 sh | −1% |
| Increased | IVERIC BIO INC (ISEE) | 0.8% | 0.6% | −0.2 pts | +33,100 sh | +2% |
| Reduced | NEVRO CORP (NVRO) | 0.9% | 0.7% | −0.2 pts | −5,500 sh | −1% |
| Increased | CENTENE CORP DEL (CNC) | 1.7% | 2.1% | +0.4 pts | +2,610 sh | 0% |
| Increased | GRITSTONE BIO INC (GRTS) | 0.9% | 0.6% | −0.2 pts | +81,022 sh | +1% |
| Reduced | REPARE THERAPEUTICS INC (RPTX) | 1.2% | 1.5% | +0.2 pts | −12,000 sh | 0% |
| Reduced | KYMERA THERAPEUTICS INC (KYMR) | 3.5% | 2.0% | −1.5 pts | −7,900 sh | 0% |
| Reduced | NURIX THERAPEUTICS INC (NRIX) | 1.3% | 1.5% | +0.1 pts | −12,100 sh | 0% |
| Reduced | AKERO THERAPEUTICS INC (AKRO) | 0.7% | 0.6% | −0.1 pts | −15,000 sh | −1% |
| Reduced | HOOKIPA PHARMA INC (HOOK) | 0.3% | 0.3% | 0.0 pts | −74,400 sh | −2% |
| Reduced | AYALA PHARMACEUTICALS INC (AYLA) | 0.1% | 0.0% | 0.0 pts | −109K sh | −24% |
| Reduced | PLIANT THERAPEUTICS INC (PLRX) | 0.7% | 0.9% | +0.3 pts | −11,800 sh | 0% |
| Increased | BIOVENTUS INC (BVS) | 0.6% | 0.3% | −0.2 pts | +9,600 sh | +1% |
| Reduced | ALLAKOS INC (ALLK) | 0.5% | 0.3% | −0.2 pts | −14,700 sh | −1% |
| Reduced | ALX ONCOLOGY HLDGS INC (ALXO) | 0.4% | 0.2% | −0.2 pts | −5,600 sh | −1% |
| Reduced | NEOLEUKIN THERAPEUTICS INC (NLTX) | 0.2% | 0.1% | −0.1 pts | −28,500 sh | −1% |
The 50 largest of 52 changes, by size of the trade. Full holdings for this quarter.
Reported by the fund in its Form 13F filed with the SEC; holdings are as of the quarter-end report date and may have changed since. For informational purposes only — not investment advice or a recommendation to buy or sell any security. FilingExplorer is not affiliated with or endorsed by this fund. How this brief is compiled
Top 10 positions — 51.8% of the equity book
Changes in the top 10 this quarter: SGEN entered · HZNP entered · REPL entered · KYMR left · ADCT left · SNCE left
| # | Security | Weight before | Weight now | |
|---|---|---|---|---|
| 1 | FATE THERAPEUTICS INC (FATE) | 15.7% | 12.3% | |
| 2 | AMICUS THERAPEUTICS INC (FOLD) | 6.6% | 9.1% | |
| 3 | SEAGEN INC (SGEN) | 2.0% | 5.8% | Entered the top 10 |
| 4 | ARGENX SE (ARGX) | 5.1% | 5.6% | |
| 5 | KRYSTAL BIOTECH INC (KRYS) | 3.8% | 4.8% | |
| 6 | LIVANOVA PLC (LIVN) | 5.0% | 3.9% | |
| 7 | HORIZON THERAPEUTICS PUB L (HZNP) | 0.0% | 2.8% | Entered the top 10 |
| 8 | BEAM THERAPEUTICS INC (BEAM) | 3.3% | 2.7% | |
| 9 | THE BEAUTY HEALTH COMPANY (SKIN) | 2.8% | 2.5% | |
| 10 | REPLIMUNE GROUP INC (REPL) | 2.0% | 2.4% | Entered the top 10 |
| — | KYMERA THERAPEUTICS INC (KYMR) | 3.5% | 2.0% | Left the top 10 |
| — | ADC THERAPEUTICS SA (ADCT) | 3.4% | 2.3% | Left the top 10 |
| — | SCIENCE 37 HOLDINGS INC (SNCE) | 3.3% | 1.5% | Left the top 10 |
Weights are each position's reported value as a share of the fund's reported equity positions (options and principal-amount holdings excluded).