RA CAPITAL MANAGEMENT L P
Q3 2024 Form 13-F

BOSTON, MASSACHUSETTS
CIK 0001346824 · CRD 160174 · SEC-registered investment adviser
$8.7B Reported Value Total

RA CAPITAL MANAGEMENT, LP reports 11 total accounts under management (AUM). There are 11 discretionary accounts valued at $12,629,842,282, and 0 non-discretionary accounts.

Source: Form ADV filed * Note that certain holdings are exempt from Form 13-F reporting, so the AUM totals may be greater than the Form 13-F total.
SEC Registered Discretionary Manager
Private funds (Form ADV)
6 funds · $16.3B gross asset value
Hedge Fund: $14.5B · Venture Capital Fund: $1.8B
Source: Form ADV filed 2026-03-31
Reported value
$8.7B
Quarter over quarter
+12.2%
Holdings
81
Top-10 concentration
55.2%

Key People

Form ADV owners & control persons
Richard H. (mi Only) Aldrich
PARTNER
Peter (nmn) Kolchinsky
PORTFOLIO MANAGER
Craig Alan Randall
GENERAL COUNSEL

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Q3 2024 13F record

Q3 2024 13F filing summary

Q3 2024 Form 13F portfolio summary
Period of report September 30, 2024
Filed November 14, 2024
Form 13F-HR
Reported value $8.7B
Positions 81
Change in reported value +14.7%
New positions 9
Exited positions 6
Position turnover 17.2%
Top-10 concentration 55.2%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 14, 2026
84 $11.5B
Q1 2026 13F
Filed May 15, 2026
85 $9.4B
Q4 2025 13F
Filed Feb 17, 2026
71 $9.8B
Q3 2025 13F
Filed Nov 14, 2025
67 $8.1B
Q2 2025 13F
Filed Aug 14, 2025
63 $5.9B
Q1 2025 13F
Filed May 15, 2025
85 $6.0B
Q4 2024 13F
Filed Feb 14, 2025
89 $7.5B
Q3 2024 13F
Filed Nov 14, 2024
81 $8.7B
Q2 2024 13F
Filed Aug 14, 2024
78 $7.6B
Q1 2024 13F
Filed May 15, 2024
76 $7.9B
Q4 2023 13F
Filed Feb 14, 2024
62 $6.4B
Q3 2023 13F
Filed Nov 14, 2023
66 $5.1B
Q2 2023 13F
Filed Aug 14, 2023
54 $5.3B
Q1 2023 13F
Filed May 15, 2023
59 $4.4B
Q4 2022 13F
Filed Feb 14, 2023
70 $4.9B
Q3 2022 13F
Filed Nov 14, 2022
81 $4.7B
Q2 2022 13F
Filed Aug 15, 2022
88 $3.8B
Q1 2022 13F
Filed May 16, 2022
96 $4.6B
Q4 2021 13F
Filed Feb 14, 2022
97 $5.7B
Q3 2021 13F
Filed Nov 15, 2021
95 $7.2B

33 earlier quarters on file — choose one from the quarter menu above.

Top 20 holdings · Q3 2024

Largest Q3 2024 13F positions by reported value
# Holding Reported value % of portfolio
1 ASND ASCENDIS PHARMA A/S - ADR $1.4B 16.72%
2 PCVX VAXCYTE INC $992.9M 11.45%
3 JANX JANUX THERAPEUTICS INC $416.4M 4.8%
4 LEGN LEGEND BIOTECH CORP-ADR $365.8M 4.22%
5 RYTM RHYTHM PHARMACEUTICALS INC $318.8M 3.68%
6 RNA AVIDITY BIOSCIENCES INC $289.4M 3.34%
7 TYRA TYRA BIOSCIENCES INC $244.9M 2.82%
8 EVH EVOLENT HEALTH INC - A $240.8M 2.78%
9 EWTX EDGEWISE THERAPEUTICS INC $237.8M 2.74%
10 BIIB BIOGEN INC $229.6M 2.65%
11 DYN DYNE THERAPEUTICS INC $229.2M 2.64%
12 RXST RXSIGHT INC $193.6M 2.23%
13 BCAX BICARA THERAPEUTICS INC $177.2M 2.04%
14 ELYM CLIMB BIO INC $159.9M 1.84%
15 SPRY ARS PHARMACEUTICALS INC $157.5M 1.82%
16 ACLX ARCELLX INC $154.6M 1.78%
17 ARTV ARTIVA BIOTHERAPEUTICS INC $152.2M 1.76%
18 WVE WAVE LIFE SCIENCES LTD $149.3M 1.72%
19 GERN GERON CORP $146.6M 1.69%
20 VRNA VERONA PHARMA PLC - ADR $144.1M 1.66%

Values as reported on the Q3 2024 Form 13F. Every position is in the holdings table below.

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