RA CAPITAL MANAGEMENT L P
Q3 2022 Form 13-F

BOSTON, MASSACHUSETTS
CIK 0001346824 · CRD 160174 · SEC-registered investment adviser
$4.7B Reported Value Total

RA CAPITAL MANAGEMENT, LP reports 9 total accounts under management (AUM). There are 9 discretionary accounts valued at $9,650,336,033, and 0 non-discretionary accounts.

Source: Form ADV filed * Note that certain holdings are exempt from Form 13-F reporting, so the AUM totals may be greater than the Form 13-F total.
SEC Registered Discretionary Manager
Private funds (Form ADV)
6 funds · $16.3B gross asset value
Hedge Fund: $14.5B · Venture Capital Fund: $1.8B
Source: Form ADV filed 2026-03-31
Reported value
$4.7B
Quarter over quarter
+21.0%
Holdings
81
Top-10 concentration
46.5%

Key People

Form ADV owners & control persons
Richard H. (mi Only) Aldrich
PARTNER
Peter (nmn) Kolchinsky
PORTFOLIO MANAGER
Craig Alan Randall
GENERAL COUNSEL

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Q3 2022 13F record

Q3 2022 13F filing summary

Q3 2022 Form 13F portfolio summary
Period of report September 30, 2022
Filed November 14, 2022
Form 13F-HR
Reported value $4.7B
Positions 81
Change in reported value +25.0%
New positions 13
Exited positions 20
Position turnover 32.7%
Top-10 concentration 46.5%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 14, 2026
84 $11.5B
Q1 2026 13F
Filed May 15, 2026
85 $9.4B
Q4 2025 13F
Filed Feb 17, 2026
71 $9.8B
Q3 2025 13F
Filed Nov 14, 2025
67 $8.1B
Q2 2025 13F
Filed Aug 14, 2025
63 $5.9B
Q1 2025 13F
Filed May 15, 2025
85 $6.0B
Q4 2024 13F
Filed Feb 14, 2025
89 $7.5B
Q3 2024 13F
Filed Nov 14, 2024
81 $8.7B
Q2 2024 13F
Filed Aug 14, 2024
78 $7.6B
Q1 2024 13F
Filed May 15, 2024
76 $7.9B
Q4 2023 13F
Filed Feb 14, 2024
62 $6.4B
Q3 2023 13F
Filed Nov 14, 2023
66 $5.1B
Q2 2023 13F
Filed Aug 14, 2023
54 $5.3B
Q1 2023 13F
Filed May 15, 2023
59 $4.4B
Q4 2022 13F
Filed Feb 14, 2023
70 $4.9B
Q3 2022 13F
Filed Nov 14, 2022
81 $4.7B
Q2 2022 13F
Filed Aug 15, 2022
88 $3.8B
Q1 2022 13F
Filed May 16, 2022
96 $4.6B
Q4 2021 13F
Filed Feb 14, 2022
97 $5.7B
Q3 2021 13F
Filed Nov 15, 2021
95 $7.2B

33 earlier quarters on file — choose one from the quarter menu above.

Top 20 holdings · Q3 2022

Largest Q3 2022 13F positions by reported value
# Holding Reported value % of portfolio
1 ASND ASCENDIS PHARMA A/S $781.5M 16.67%
2 BIIB BIOGEN INC $250.3M 5.34%
3 CTKB CYTEK BIOSCIENCES INC $197.0M 4.2%
4 FMTX FORMA THERAPEUTICS HLDGS INC $179.8M 3.84%
5 DAWN DAY ONE BIOPHARMACEUTICALS I $141.0M 3.01%
6 AVTE AEROVATE THERAPEUTICS INC $137.0M 2.92%
7 RYTM RHYTHM PHARMACEUTICALS INC $134.0M 2.86%
8 TVTX TRAVERE THERAPEUTICS INC $121.3M 2.59%
9 BLU BELLUS HEALTH INC NEW $120.2M 2.56%
10 JANX JANUX THERAPEUTICS INC $117.4M 2.5%
11 PCVX VAXCYTE INC $109.9M 2.35%
12 DICE DICE THERAPEUTICS INC $105.6M 2.25%
13 IMGN IMMUNOGEN INC $103.9M 2.22%
14 NKTX NKARTA INC $102.7M 2.19%
15 ABOS ACUMEN PHARMACEUTICALS INC $98.0M 2.09%
16 LEGN LEGEND BIOTECH CORP $95.4M 2.04%
17 ITOS ITEOS THERAPEUTICS INC $84.1M 1.8%
18 RLMD RELMADA THERAPEUTICS INC $74.0M 1.58%
19 PEPG PEPGEN INC $73.8M 1.58%
20 GERN GERON CORP $70.5M 1.5%

Values as reported on the Q3 2022 Form 13F. Every position is in the holdings table below.

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