ENAVATE SCIENCES GP LLC
Q4 2025 Form 13-F

NEW YORK, DELAWARE
CIK 0001953107 · Institutional investment manager
$506.8M Reported Value Total
Reported value
$506.8M
Quarter over quarter
+54.4%
Holdings
7
Top-10 concentration
100.0%

Key People

Named on the latest Form 13-F filing — not necessarily an owner
James P. Boylan
Chief Executive Officer

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Q4 2025 13F record

Q4 2025 13F filing summary

Q4 2025 Form 13F portfolio summary
Period of report December 31, 2025
Filed February 17, 2026
Form 13F-HR
Reported value $506.8M
Positions 7
Change in reported value +54.7%
New positions 0
Exited positions 0
Position turnover 0.0%
Top-10 concentration 100.0%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 14, 2026
7 $345.4M
Q1 2026 13F
Filed May 15, 2026
7 $351.5M
Q4 2025 13F
Filed Feb 17, 2026
7 $506.8M
Q3 2025 13F
Filed Nov 14, 2025
7 $327.5M
Q2 2025 13F
Filed Aug 14, 2025
6 $176.5M
Q1 2025 13F
Filed May 15, 2025
6 $132.7M
Q4 2024 13F
Filed Feb 14, 2025
5 $139.2M

Top 7 holdings · Q4 2025

Largest Q4 2025 13F positions by reported value
# Holding Reported value % of portfolio
1 ZBIO ZENAS BIOPHARMA INC $142.3M 28.08%
2 IMNM IMMUNOME INC $102.4M 20.21%
3 SION SIONNA THERAPEUTICS INC $101.9M 20.12%
4 UPB UPSTREAM BIO INC $66.8M 13.18%
5 CMPX COMPASS THERAPEUTICS INC $41.8M 8.25%
6 BBOT BRIDGEBIO ONCOLOGY THERAPEUT $32.9M 6.49%
7 CAMP CAMP4 THERAPEUTICS CORP $18.6M 3.67%

Values as reported on the Q4 2025 Form 13F. Every position is in the holdings table below.

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