BVF INC IL
Q4 2025 Form 13-F

SAN FRANCISCO, CALIFORNIA
CIK 0001056807 · Institutional investment manager
Consolidated report · includes 1 manager since Q2 2013
$3.0B Reported Value Total
Reported value
$3.0B
Quarter over quarter
+41.9%
Holdings
41
Top-10 concentration
62.8%

Filing Structure

Reports holdings for

Key People

Named on the latest Form 13-F filing — not necessarily an owner
Mark N. Lampert
President

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Q4 2025 13F record

Q4 2025 13F filing summary

Q4 2025 Form 13F portfolio summary
Period of report December 31, 2025
Filed February 17, 2026
Form 13F-HR
Reported value $3.0B
Positions 41
Change in reported value +20.4%
New positions 2
Exited positions 7
Position turnover 18.8%
Top-10 concentration 62.8%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 14, 2026
44 $3.9B
Q1 2026 13F
Filed May 15, 2026
41 $3.1B
Q4 2025 13F
Filed Feb 17, 2026
41 $3.0B
Q3 2025 13F
Filed Nov 14, 2025
46 $2.5B
Q2 2025 13F
Filed Aug 14, 2025
44 $2.8B
Q1 2025 13F
Filed May 15, 2025
51 $2.5B
Q4 2024 13F
Filed Feb 14, 2025
53 $3.0B
Q3 2024 13F
Filed Nov 14, 2024
55 $3.4B
Q2 2024 13F
Filed Aug 14, 2024
60 $3.6B
Q1 2024 13F
Filed May 15, 2024
62 $3.6B
Q4 2023 13F
Filed Feb 14, 2024
70 $4.0B
Q3 2023 13F
Filed Nov 14, 2023
69 $3.7B
Q2 2023 13F
Filed Aug 14, 2023
67 $3.6B
Q1 2023 13F
Filed May 15, 2023
72 $2.7B
Q4 2022 13F
Filed Feb 14, 2023
78 $2.4B
Q3 2022 13F
Filed Nov 14, 2022
80 $2.4B
Q2 2022 13F
Filed Aug 15, 2022
79 $2.1B
Q1 2022 13F
Filed May 16, 2022
81 $2.5B
Q4 2021 13F
Filed Feb 14, 2022
83 $2.8B
Q3 2021 13F
Filed Nov 15, 2021
75 $2.6B

33 earlier quarters on file — choose one from the quarter menu above.

Top 20 holdings · Q4 2025

Largest Q4 2025 13F positions by reported value
# Holding Reported value % of portfolio
1 KYMR KYMERA THERAPEUTICS INC $428.2M 14.41%
2 RVMD REVOLUTION MEDICINES INC $267.4M 9.0%
3 MLTX MOONLAKE IMMUNOTHERAPEUTICS $260.3M 8.76%
4 GPCR STRUCTURE THERAPEUTICS INC $242.0M 8.15%
5 OLMA OLEMA PHARMACEUTICALS INC $132.4M 4.46%
6 MIRM MIRUM PHARMACEUTICALS INC $118.1M 3.98%
7 GHRS GH RESEARCH PLC $112.1M 3.77%
8 XNCR XENCOR INC $109.2M 3.68%
9 ZYME ZYMEWORKS INC $103.7M 3.49%
10 PVLA PALVELLA THERAPEUTICS INC NE $92.0M 3.1%
11 KURA KURA ONCOLOGY INC $89.5M 3.01%
12 STOK STOKE THERAPEUTICS INC $71.9M 2.42%
13 XOMA XOMA ROYALTY CORPORATION $68.9M 2.32%
14 ABVX ABIVAX SA $68.5M 2.31%
15 NKTR NEKTAR THERAPEUTICS $65.9M 2.22%
16 ACIU AC IMMUNE SA $62.2M 2.1%
17 GLUE MONTE ROSA THERAPEUTICS INC $60.1M 2.02%
18 CGEM CULLINAN THERAPEUTICS INC $59.5M 2.0%
19 TYRA TYRA BIOSCIENCES INC $55.9M 1.88%
20 IRON DISC MEDICINE INC $51.6M 1.74%

Values as reported on the Q4 2025 Form 13F. Every position is in the holdings table below.

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