BRAIDWELL LP
Q1 2025 Form 13-F

STAMFORD, CONNECTICUT
CIK 0001920938 · CRD 316988 · SEC-registered investment adviser
$2.8B Reported Value Total

BRAIDWELL LP reports 12 total accounts under management (AUM). There are 12 discretionary accounts valued at $5,228,467,000, and 0 non-discretionary accounts.

Source: Form ADV filed * Note that certain holdings are exempt from Form 13-F reporting, so the AUM totals may be greater than the Form 13-F total.
SEC Registered Discretionary Manager
Private funds (Form ADV)
13 funds · $3.6B gross asset value
Hedge Fund: $3.6B · Private Equity Fund: $0
Source: Form ADV filed 2026-09-22
Reported value
$2.8B
Quarter over quarter
-9.3%
Holdings
52
Top-10 concentration
40.1%

Key People

Form ADV owners & control persons
Alexander Thomas Karnal
MANAGING MEMBER
Brian James Kreiter
MANAGING MEMBER
Ken C Joseph
CHIEF COMPLIANCE OFFICER

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13F Metrics

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Q1 2025 13F record

Q1 2025 13F filing summary

Q1 2025 Form 13F portfolio summary
Period of report March 31, 2025
Filed May 15, 2025
Form 13F-HR
Reported value $2.8B
Positions 52
Change in reported value -15.7%
New positions 13
Exited positions 22
Position turnover 47.3%
Top-10 concentration 40.1%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 14, 2026
83 $2.7B
Q1 2026 13F
Filed May 15, 2026
82 $3.0B
Q4 2025 13F
Filed Feb 17, 2026
68 $3.1B
Q3 2025 13F
Filed Nov 14, 2025
64 $3.4B
Q2 2025 13F
Filed Aug 14, 2025
45 $2.9B
Q1 2025 13F
Filed May 15, 2025
52 $2.8B
Q4 2024 13F
Filed Feb 14, 2025
59 $3.4B
Q3 2024 13F
Filed Nov 14, 2024
65 $3.5B
Q2 2024 13F
Filed Aug 14, 2024
58 $3.2B
Q1 2024 13F
Filed May 15, 2024
51 $3.1B
Q4 2023 13F
Filed Feb 14, 2024
47 $2.7B
Q3 2023 13F
Filed Nov 14, 2023
60 $3.2B
Q2 2023 13F
Filed Aug 14, 2023
58 $3.1B
Q1 2023 13F
Filed May 15, 2023
57 $3.0B
Q4 2022 13F
Filed Feb 14, 2023
63 $3.0B

Top 20 holdings · Q1 2025

Largest Q1 2025 13F positions by reported value
# Holding Reported value % of portfolio
1 GH 1.25 02/15/31 GUARDANT HEALTH INC $227.4M 7.99%
2 NVCR 0 11/01/25 NOVOCURE LTD $136.6M 4.8%
3 NBIX NEUROCRINE BIOSCIENCES INC $131.8M 4.63%
4 LEGN LEGEND BIOTECH CORP $101.0M 3.55%
5 RGEN 1 12/15/28 REPLIGEN CORP $95.8M 3.37%
6 ARGX ARGENX SE $95.2M 3.35%
7 XENE XENON PHARMACEUTICALS INC $90.9M 3.2%
8 IRTC 1.5 09/01/29 IRHYTHM TECHNOLOGIES INC $89.7M 3.15%
9 NEO 0.25 01/15/28 NEOGENOMICS INC $87.9M 3.09%
10 ALGN ALIGN TECHNOLOGY INC $84.3M 2.96%
11 IRWD 1.5 06/15/26 IRONWOOD PHARMACEUTICALS INC $82.5M 2.9%
12 CGON CG ONCOLOGY INC $80.4M 2.83%
13 KRYS KRYSTAL BIOTECH INC $72.3M 2.54%
14 BBIO 2.5 03/15/27 BRIDGEBIO PHARMA INC $72.0M 2.53%
15 TMO THERMO FISHER SCIENTIFIC INC $63.6M 2.23%
16 DHR DANAHER CORPORATION $63.4M 2.23%
17 GKOS GLAUKOS CORP $61.5M 2.16%
18 NUVL NUVALENT INC $59.6M 2.1%
19 IRTC IRHYTHM TECHNOLOGIES INC $58.2M 2.05%
20 APGE APOGEE THERAPEUTICS INC $57.5M 2.02%

Values as reported on the Q1 2025 Form 13F. Every position is in the holdings table below.

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