ARTAL GROUP S A
Q4 2022 Form 13-F

LUXEMBOURG
CIK 0001053906 · Institutional investment manager
Consolidated report · includes 5 managers since Q2 2013
$1.8B Reported Value Total
Reported value
$1.8B
Quarter over quarter
-11.1%
Holdings
125
Top-10 concentration
44.3%

Reports holdings for

  • Invus Public Equities Advisors LLC · File #028-11522 · Q2 2013 – Q2 2024
  • Artal Luxembourg S A · File #028-19506 · Q1 2019 – Q1 2023
  • Artal Treasury Ltd (not a 13F filer in our records) · File #028-19088 · Q4 2018 – Q4 2021
  • Invus Advisors, L.L.C. (not a 13F filer in our records) · File #028-14596 · Q2 2013 – Q3 2013

Key People

Named on the latest Form 13-F filing — not necessarily an owner
Anne Goffard
Authorized Person

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Q4 2022 13F record

Q4 2022 13F filing summary

Q4 2022 Form 13F portfolio summary
Period of report December 31, 2022
Filed February 13, 2023
Form 13F-HR
Reported value $1.8B
Positions 125
Change in reported value -23.5%
New positions 11
Exited positions 16
Position turnover 19.2%
Top-10 concentration 44.3%

13F filings by quarter

Form 13F filings by quarter
Quarter Positions Value
Q2 2026 13F
Filed Aug 13, 2026
2 $931.1M
Q1 2026 13F
Filed May 14, 2026
2 $1.0B
Q4 2025 13F
Filed Feb 12, 2026
2 $714.6M
Q3 2025 13F
Filed Nov 12, 2025
2 $758.2M
Q2 2025 13F
Filed Aug 13, 2025
2 $930.2M
Q1 2025 13F
Filed May 14, 2025
2 $884.2M
Q4 2024 13F
Filed Feb 14, 2025
2 $1.2B
Q3 2024 13F
Filed Nov 13, 2024
2 $2.4B
Q2 2024 13F
Filed Aug 14, 2024
109 $3.9B
Q1 2024 13F
Filed May 13, 2024
107 $3.9B
Q4 2023 13F
Filed Feb 9, 2024
91 $3.0B
Q3 2023 13F
Filed Nov 13, 2023
101 $2.3B
Q2 2023 13F
Filed Aug 11, 2023
114 $3.2B
Q1 2023 13F
Filed May 12, 2023
118 $1.7B
Q4 2022 13F
Filed Feb 13, 2023
125 $1.8B
Q3 2022 13F
Filed Nov 14, 2022
130 $2.3B
Q2 2022 13F
Filed Aug 11, 2022
132 $1.9B
Q1 2022 13F
Filed May 12, 2022
135 $2.4B
Q4 2021 13F
Filed Feb 11, 2022
144 $3.7B
Q3 2021 13F
Filed Nov 12, 2021
140 $4.5B

33 earlier quarters on file — choose one from the quarter menu above.

Top 20 holdings · Q4 2022

Largest Q4 2022 13F positions by reported value
# Holding Reported value % of portfolio
1 LXRX LEXICON PHARMACEUTICALS INC $171.5M 9.57%
2 ONC BEIGENE LTD $132.0M 7.37%
3 MRTX MIRATI THERAPEUTICS INC $83.0M 4.64%
4 SRRK SCHOLAR ROCK HLDG CORP $81.3M 4.54%
5 CERE CEREVEL THERAPEUTICS HLDNG I $59.9M 3.34%
6 MORF MORPHIC HLDG INC $57.5M 3.21%
7 WGHTQ WW INTL INC $57.2M 3.19%
8 SWTX SPRINGWORKS THERAPEUTICS INC $52.0M 2.9%
9 KYMR KYMERA THERAPEUTICS INC $49.9M 2.79%
10 FOLD AMICUS THERAPEUTICS INC $48.8M 2.73%
11 APLS APELLIS PHARMACEUTICALS INC $46.5M 2.6%
12 CYTK CYTOKINETICS INC $45.8M 2.56%
13 IGMS IGM BIOSCIENCES INC $41.7M 2.33%
14 AGEN AGENUS INC $34.8M 1.94%
15 KRYS KRYSTAL BIOTECH INC $31.7M 1.77%
16 BLU BELLUS HEALTH INC NEW $30.4M 1.7%
17 KRTX KARUNA THERAPEUTICS INC $29.5M 1.65%
18 ALVR ALLOVIR INC $28.6M 1.6%
19 SAGE SAGE THERAPEUTICS INC $28.6M 1.6%
20 VIGL VIGIL NEUROSCIENCE INC $28.0M 1.57%

Values as reported on the Q4 2022 Form 13F. Every position is in the holdings table below.

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